Monica M Montano Selected Research

acetamide

1/2022	Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1.
12/2019	Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells.
3/2014	Lead optimization of HMBA to develop potent HEXIM1 inducers.
12/2013	HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability.
2/2008	Mutation of the HEXIM1 gene results in defects during heart and vascular development partly through downregulation of vascular endothelial growth factor.

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Monica M Montano Research Topics

Disease

13	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2003
11	Neoplasms (Cancer) 01/2022 - 07/2003
6	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 03/2014
4	Triple Negative Breast Neoplasms 12/2020 - 01/2015
3	Carcinogenesis 10/2012 - 08/2005
2	Neoplasm Metastasis (Metastasis) 12/2019 - 01/2016
2	Leukemia 01/2019 - 08/2011
2	Thrombocytopenia (Thrombopenia) 01/2016 - 08/2011
1	Melanoma (Melanoma, Malignant) 12/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2015
1	Hypoxia (Hypoxemia) 12/2013
1	Hypertrophy 07/2013
1	Hyperplasia 10/2012

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2003
6	hexamethylene bisacetamide (HMBA)IBA 12/2020 - 08/2011
5	acetamideIBA 01/2022 - 02/2008
5	Estrogen Receptor alphaIBA 01/2022 - 07/2003
5	Estrogens (Estrogen)FDA Link 10/2012 - 07/2003
4	Estrogen ReceptorsIBA 01/2022 - 07/2003
4	Tamoxifen FDA LinkGeneric 01/2016 - 07/2003
2	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 01/2022
2	Histone DemethylasesIBA 12/2019 - 11/2019
2	Phenobarbital (Luminal)FDA Link 11/2019 - 06/2010
2	Chalcone (Benzalacetophenone)IBA 01/2019 - 01/2019
2	AndrogensIBA 07/2018 - 09/2014
2	Transcription Factors (Transcription Factor)IBA 07/2013 - 02/2008
2	Selective Estrogen Receptor Modulators (SERM)IBA 10/2012 - 01/2012
2	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA 10/2012 - 05/2005
2	EnzymesIBA 01/2012 - 05/2005
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2005 - 07/2003
2	Estrogen Receptor Modulators (Antiestrogen)IBA 05/2005 - 07/2003
2	Estrogen Receptor betaIBA 01/2005 - 07/2003
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	LigandsIBA 01/2022
1	MethyltransferasesIBA 01/2022
1	Positive Transcriptional Elongation Factor BIBA 01/2022
1	Decitabine FDA Link 12/2020
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 12/2019
1	histone H3 trimethyl Lys4IBA 12/2019
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 11/2019
1	norwogoninIBA 04/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	OxadiazolesIBA 01/2019
1	quinolineIBA 01/2019
1	Adenosine Triphosphate (ATP)IBA 09/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 09/2015
1	Temozolomide (Temodar)FDA LinkGeneric 01/2015
1	Alkylating AgentsIBA 01/2015
1	Messenger RNA (mRNA)IBA 09/2014
1	bicalutamide (Casodex)FDA LinkGeneric 09/2014
1	Doxycycline (Periostat)FDA LinkGeneric 10/2012
1	Aromatase (CYP19)IBA 10/2012
1	NAD (NADH)IBA 10/2012
1	Antineoplastic Agents (Antineoplastics)IBA 08/2011
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 02/2008
1	AntioxidantsIBA 05/2005
1	CarcinogensIBA 05/2005
1	Therapeutic UsesIBA 05/2005
1	Phytoestrogens (Phytoestrogen)IBA 01/2005
1	biochanin AIBA 01/2005
1	GenisteinIBA 01/2005
1	ResveratrolIBA 01/2005
1	afimoxifene (hydroxytamoxifen)IBA 07/2003
1	Raloxifene Hydrochloride (Evista)FDA Link 07/2003

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 12/2019
1	Castration 09/2014